In the diagnosis and treatment of tuberculosis (tuberculosis, TB), especially multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis, the rapid and accurate identification of Mycobacterium tuberculosis and its drug resistance genes is crucial.The use of molecular biology techniques to detect drug-resistant genotypes of tuberculosis has become one of the diagnostic methods for drug-resistant tuberculosis.Compared with classic PCR and mNGS products, tNGS technology can widely cover drug-resistant genes and mutation sites of various anti-tuberculosis drugs, with high sensitivity and good timeliness, and can be used as a rapid screening method for drug-resistant tuberculosis and/or traditional An effective supplement to drug susceptibility testing.


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