Recently, Professor Xu Tianmin’s team from the Department of Infectious Diseases of Changzhou Third People’s Hospital cooperated with Difei Medical and published a rare case report in the journal BMC Infectious Diseases (IF=3.7) in January 24. The patient’s central nervous system and blood system were combined with infection due to EV. Hepatitis virus (HEV) and Klebsiella pneumoniae, mNGS has outstanding advantages in the diagnosis of mixed infections.

Recently, the team of Director Miao Yun of the Transplantation Department of Nanfang Hospital collaborated with Diffei Medical to prospectively collect clinical samples from 40 perioperative kidney transplant patients who underwent hemodialysis catheter removal for mNGS detection and culture.The positive detection rates of bacteria by mNGS and traditional culture were 97.09% (200/206) and 2.65% (3/113), respectively.At the same time, the study describes the microbial structure and diversity at the tip of hemodialysis catheters in dialysis patients during the perioperative period of kidney transplantation, filling the gap in the colonization microbial database in hemodialysis catheters.The research results were published in Renal Failure.

Mycoplasma pneumoniae is one of the common pathogens of pulmonary infection in children, and humans are the only host.Mycoplasma pneumoniae pneumonia is a common community-acquired pneumonia in school-age children, accounting for 10%-40% of CAP in hospitalized children.In the early stage, due to macrolide resistance and a series of complex mechanisms, the incidence of refractory Mycoplasma pneumoniae pneumonia continued to increase, often leading to poor prognosis and sequelae such as atelectasis, pulmonary necrosis, bronchiectasis, and bronchiolitis obliterans. .Some studies have found that the microbiota changes significantly during lower respiratory tract infection, which is closely related to the prognosis or course of pneumonia.This study conducted mNGS pathogenic examination on bronchoalveolar lavage fluid from children diagnosed with RMPP or non-refractory Mycoplasma pneumoniae pneumonia (NRMPP), and analyzed the relationship between the lower respiratory tract microbiota and RMPP. The relevant research results were published in Translational Pediatrics.