2023-08-02 Recently, the Department of Respiratory Medicine, West China Fourth Hospital of Sichuan University, in cooperation with Difei Medical, published a retrospective study on pneumoconiosis in Frontiers in Cellular and Infection Microbiology (IF=6.073).In this paper, 120 patients with suspected pneumoconiosis complicated with pulmonary infection were screened, and 44 eligible patients were finally included. The corresponding BALF samples were collected for metagenomic next-generation sequencing (mNGS), which fully revealed the lung disease of patients with pneumoconiosis complicated with infection (group P). The lung microbiome was compared between the P group and non-pneumoconiosis patients with infection (non-P group) to explore potential biomarkers.