Precision medicine, testing first.On March 18, at the 2023EBC Eighth Yimao Bio Industry Conference, MGI held the 'DNBSEQ-G99 Signing Ceremony'.DiFei Medical and MGI have officially reached a cooperation to jointly develop G99-based application expansion to facilitate accurate detection of infectious pathogens and empower high-quality clinical development!

From July 28 to July 30, 2023, the 'Third Beijing-Tianjin-Hebei Canal Breathing Forum' was successfully held.Focusing on hot issues in the field of chest diseases and respiratory critical illnesses, this forum brought together domestic experts and scholars in research fields such as respiratory, infection, and critical care medicine, as well as scientific researchers and medical and health managers from all over the world. New knowledge, new ideas and new technologies in the field of critical care, promote academic exchanges and cooperation, and actively promote academic development.

On June 20, 2023, led by Zhongshan Hospital Affiliated to Fudan University and jointly participated by Difei Medical, the 'Research on Accurate Early Diagnosis and Severe Early Warning of Acute Respiratory Infectious Diseases' and 'Building of a Multidisciplinary Cooperative Diagnosis and Treatment System for Severe Pneumonia 'The mid-term communication meeting of the multi-center clinical research project of the two major subjects was successfully held in Shanghai.

Recently, Professor Xu Tianmin’s team from the Department of Infectious Diseases of Changzhou Third People’s Hospital cooperated with Difei Medical and published a rare case report in the journal BMC Infectious Diseases (IF=3.7) in January 24. The patient’s central nervous system and blood system were combined with infection due to EV. Hepatitis virus (HEV) and Klebsiella pneumoniae, mNGS has outstanding advantages in the diagnosis of mixed infections.

Recently, the team of Director Miao Yun of the Transplantation Department of Nanfang Hospital collaborated with Diffei Medical to prospectively collect clinical samples from 40 perioperative kidney transplant patients who underwent hemodialysis catheter removal for mNGS detection and culture.The positive detection rates of bacteria by mNGS and traditional culture were 97.09% (200/206) and 2.65% (3/113), respectively.At the same time, the study describes the microbial structure and diversity at the tip of hemodialysis catheters in dialysis patients during the perioperative period of kidney transplantation, filling the gap in the colonization microbial database in hemodialysis catheters.The research results were published in Renal Failure.

Mycoplasma pneumoniae is one of the common pathogens of pulmonary infection in children, and humans are the only host.Mycoplasma pneumoniae pneumonia is a common community-acquired pneumonia in school-age children, accounting for 10%-40% of CAP in hospitalized children.In the early stage, due to macrolide resistance and a series of complex mechanisms, the incidence of refractory Mycoplasma pneumoniae pneumonia continued to increase, often leading to poor prognosis and sequelae such as atelectasis, pulmonary necrosis, bronchiectasis, and bronchiolitis obliterans. .Some studies have found that the microbiota changes significantly during lower respiratory tract infection, which is closely related to the prognosis or course of pneumonia.This study conducted mNGS pathogenic examination on bronchoalveolar lavage fluid from children diagnosed with RMPP or non-refractory Mycoplasma pneumoniae pneumonia (NRMPP), and analyzed the relationship between the lower respiratory tract microbiota and RMPP. The relevant research results were published in Translational Pediatrics.